Alzheimer’s disease may be a new, third type of diabetes that shares common features of type 1 and type 2 diabetes, according to a new study.
Researchers found that insulin and the cells that process it in the brain drop sharply in the early stages of Alzheimer’s disease. They also found that insulin levels continue to decline as the disease progresses and becomes more severe.
“Insulin disappears early and dramatically in Alzheimer’s disease. And many of the unexplained features of Alzheimer’s, such as cell death and tangles in the brain, appear to be linked to abnormalities in insulin signaling. This demonstrates that the disease is most likely a neuroendocrine disorder, or another type of diabetes,” says researcher Suzanne M. de la Monte, professor of pathology at Brown Medical School, in a news release.
Author: NewMexiKen
‘I never wanted to kill anybody, but if a man had it in his mind to kill me, I made it my business to get him first.’
The History Channel tells the fascinating story of Elfego Baca for This Day in Old West History — December 1, 1884:
Elfego Baca, legendary defender of southwestern Hispanos, manages to hold off a gang of 80 cowboys who are determined to kill him.
The trouble began the previous day, when Baca arrested Charles McCarthy, a cowboy who fired five shots at him in a Frisco (now Reserve), New Mexico, saloon. For months, a vicious band of Texan cowboys had terrorized the Hispanos of Frisco, brutally castrating one young Mexican man and using another for target practice. Outraged by these abuses, Baca gained a commission as deputy sheriff to try to end the terror. His arrest of McCarthy served notice to other Anglo cowboys that further abuses of the Hispanos would not be tolerated.
The Texans, however, were not easily intimidated. The morning after McCarthy’s arrest, a group of about 80 cowboys rode into town to free McCarthy and make an example of Baca for all Mexicans. Baca gathered the women and children of the town in a church for their safety and prepared to make a stand. When he saw how outnumbered he was, Baca retreated to an adobe house, where he killed one attacker and wounded several others. The irate cowboys peppered Baca’s tiny hideout with bullets, firing about 400 rounds into the flimsy structure. As night fell, they assumed they had killed the defiant deputy sheriff, but the next morning they awoke to the smell of beef stew and tortillas–Baca was fixing his breakfast.
A short while later, two lawmen and several of Baca’s friends came to his aid, and the cowboys retreated. Baca turned himself over to the officers, and he was charged with the murder of one of the cowboys. In his trial in Albuquerque, the jury found Baca not guilty because he had acted in self-defense, and he was released to a hero’s welcome among the Hispanos of New Mexico. Baca was adored because he had taken a stand against the abusive and racist Anglo newcomers. Hugely popular, Baca later enjoyed a successful career as a lawyer, private detective, and politician in Albuquerque.
Baca was 19 at the time of the shootout and lived until 1945. In 1958, Walt Disney Studios produced The Nine Lives of Elfego Baca. Robert Loggia played the title role, with a cast that included Annette Funicello (as Chiquita), James Coburn and Alan Hale, Jr. (Gilligan’s skipper).
A golf tournament of sorts, the annual Elfego Baca Golf Shoot in Socorro, New Mexico, celebrates the deputy — “competitors are loaded into four-wheel drive vehicles to ascend Socorro Peak, 7,243 feet above sea level. Here they will battle in a one-hole shoot. The hole, a fifty foot patch of dirt, is located on the New Mexico Tech campus, about 4 hours long, 2550 feet down, and almost three miles away.”
You can read more about Elfego Baca here.
[Reposted from December 1, 2003.]
27 years ago today
President Jimmy Carter took abrupt and sweeping action to preserve 17 endangered areas of Alaska. Carter used the 1906 Antiquities Act to prevent exploitation while Congress deliberated.
Admiralty Island National Monument
Aniakchak National Monument
Becharof National Monument
Bering Land Bridge National Monument
Cape Krusenstern National Monument
Denali National Monument
Gates of the Arctic National Monument
Enlarging the Glacier Bay National Monument
Enlarging the Katmai National Monument
Kenai Fjords National Monument
Kobuk Valley National Monument
Lake Clark National Monument
Misty Fiords National Monument
Noatak National Monument
Wrangell-St. Elias National Monument
Yukon-Charley National Monument
Yukon Flats National Monument
Here’s Jay
- Only in America—even though [Congressman Cunningham] stole 2.4 million he has agreed to pay back 1.8 million to make it right. So let that be a lesson to all you other congressmen out there. If you get caught stealing you may have to pay back a small fraction of what you took.
- Don’t you love how our system works? So if you’re poor and you steal a loaf of bread it’s a $200 fine; if you’re a congressman who steals $2.4 million you get to keep a 25% bonus.
Jay Leno
Kansas (the band) accepts Intelligent Design
Check it out at Pharyngula.
Allen Stewart Konigsberg
… was born in Brooklyn on this date in 1935.
That makes Woody Allen 70 today.
Richard Pryor is 65.
Bette Midler is 60.
Fifty years ago today
As told by the Library of Congress:
On the evening of December 1, 1955, Rosa Parks, an African American, was arrested for disobeying an Alabama law requiring black passengers to relinquish seats to white passengers when the bus was full. Blacks were also required to sit at the back of the bus. Her arrest sparked a 381-day boycott of the Montgomery bus system and led to a 1956 Supreme Court decision banning segregation on public transportation.
Although her arrest was not “planned,” Park’s action was consistent with the NAACP’s desire to challenge segregated public transport in the courts. A one-day bus boycott coinciding with Parks’s December 5 court date resulted in an overwhelming African American boycott of the bus system. Since black people constituted seventy percent of the transit system’s riders, most busses carried few passengers that day.
Success demanded sustained action. Religious and political leaders met at the Dexter Avenue Baptist Church and formed the Montgomery Improvement Association (later the Southern Christian Leadership Conference) and Dexter’s new pastor, Rev. Martin Luther King, Jr., was appointed the group’s leader. For the next year, the Montgomery Improvement Association coordinated the bus boycott and the eloquent young preacher inspired those who refused to ride:
If we are wrong—the Supreme Court of this nation is wrong. If we are wrong—God almighty is wrong! If we are wrong—Jesus of Nazareth was merely a utopian dreamer and never came down to earth. If we are wrong—justice is a lie. And we are determined here in Montgomery to work and fight until justice runs down like water and righteousness like a mighty stream.Reverend Martin Luther King, Jr., Montgomery, Alabama, 1955.
The richest and poorest counties
Median household income 2003 (Census Bureau)
Top 10
- Los Alamos County, N.M. $93,089
- Douglas County, Co. 92,732
- Loudoun County, Va. 89,890
- Hunterdon County, N.J. 84,016
- Fairfax County, Va. 82,481
- Hamilton County, Ind. 80,691
- Morris County, N.J. 79,977
- Howard County, Md. 79,455
- Somerset County, N.J. 77,988
- Montgomery County, Md. 76,546
Bottom 10
- Wilcox County, Ala. $19,524
- Hancock County, Tenn. 19,228
- Starr County, Texas 19,127
- Holmes County, Miss. 19,057
- Clay County, Ky. 18,724
- Zavala County, Texas 18,553
- McDowell County, W.Va. 18,344
- Ziebach County, S.D. 17,753
- Owsley County, Ky. 17,344
- Buffalo County, S.D. 17,003
Among the states Connecticut had the highest state household median at $56,409, edging out New Jersey at $56,356. New Mexico was 45th at $35,091. Mississippi 50th at $32,397.
I think he likes it
We’ve been testing this new iMac, and our verdict is that it’s the gold standard of desktop PCs. To put it simply: No desktop offered by Dell or Hewlett-Packard or Sony or Gateway can match the new iMac G5’s combination of power, elegance, simplicity, ease of use, built-in software, stability and security. From setup to performing the most intense tasks, it’s a pleasure to use. And, contrary to common misconceptions, this Mac is competitively priced, when compared with comparably equipped midrange Windows PCs; and it handles all common Windows files, as well as the Internet and email, with aplomb.
…The combination of the new, improved hardware, plus Front Row, makes the iMac G5 the best consumer desktop you can buy this holiday season, period. For mainstream consumers doing typical tasks — Web surfing, email, office productivity, photos, music, home videos, etc. — it’s the finest desktop PC on the market, at any price. Hard-core game players, stock-market day traders, serious video producers and some other niche users should look for other computers. But, for most people, the new iMac G5 is the best choice.
Theologians to ask Pope to suspend limbo?
Limbo — the place where the Catholic Church teaches that babies go if they die before being baptized — may have its days numbered.
According to Italian media reports on Tuesday, an international theological commission will advise Pope Benedict to eliminate the teaching about limbo from the Catholic catechism.
…In his Divine Comedy, Dante passes limbo on his way into hell and writes: “Great grief seized on my own heart when this I heard, because some people of much worthiness I knew, who in limbo were suspended.”
Reuters via Yahoo! News
At first NewMexiKen thought they meant the dance.
The 10 Best Books of 2005
The New York Times publishes its choices, five fiction, five non-fiction.
Shame
From this day forward, the Democratic Party will commit to putting up a “Shame on You” billboard in the home district of any Republican who attacks a veteran’s service in order to score political points.
The first billboard will go up near Jean Schmidt’s district office in Portsmouth, Ohio. The message: “Shame on You, Jean Schmidt: Stop Attacking Veterans. Keep Your Eye on the Ball — We Need a Real Plan for Iraq”.
From, the Democratic Party, which would welcome your contribution toward the billboard.
Walk the Ray
Michael Bérubé has an insightful review of Walk the Line and similar music biopics (Ray, Coal Miner’s Daughter, etc.).
Well worth a click.
Rattlesnake Lawyer
NewMexiKen became intrigued at a book-signing Friday evening in Albuquerque’s newest Borders (on the westside at Coors Bypass and Ellison). The author, Jonathan Miller, looking a little forlorn in the mostly empty bookstore, told me proudly that The Albuquerque Journal had written that he “may just be the next John Grisham.” So I bought one of the two novels displayed on the little table — Rattlesnake Lawyer — and Miller signed it for me.
The story centers around Dan Shepard, a recent and somewhat unambitious lawyer who ends up in New Mexico as the junior public defender in an fictional eastern county. As the “baby lawyer,” he is assigned the case of a minor, Jesus Villalobos — Hay-Zeus, not Jee-zus, Shepard learns. The kid, a known troublemaker is accused of battery. The charge turns into murder when the victim dies and Miller tells the story all the way through the boy’s trial as an adult.
NewMexiKen read the book in one day, finding the characterizations and the story intriguing. A good hook, in other words. I cannot be certain that Miller gets all the details right — I doubt you can find any rattlesnakes to kill in early January, for example — but most of what he describes — the people, the community, the one-mall town, the everyone-knows-everyone sense of it, the police and prosecutors — all ring true. A reader will not confuse the setting or the characters with any place other than New Mexico, that much is for sure.
Miller has a second novel — Crater County — also published last year. Rattlesnake Lawyer was good enough I’ll look for this second one, too, even if Miller isn’t around to sign it.
Miller, who’s business card says “Attorney/Author,” attended the Albuquerque Academy. Locals will appreciate the name of one incidental character — Juan Tabo.
Update: Miller emails to say he’d been at Borders eight hours and “sold 62 books, one of the most for a one day signing by an independent author in NM.”
Best line of the day, so far
“When did everybody get the un-American idea that the president is answerable to America?”
Maureen Dowd channeling Dick Cheney.
It’s the birthday
… of America’s oldest teenager. Dick Clark is 76.
… of movie director Ridley Scott. He’s 68.
… of Ben Stiller. He’s 40.
… of Sandra Oh. The actress (Sideways, Arli$$, Grey’s Anatomy) is 35.
Winston Churchill was born on this date in 1874; he died in 1965.
Churchillian quotes:
“A fanatic is one who can’t change his mind and won’t change the subject.”
“Courage is what it takes to stand up and speak; courage is also what it takes to sit down and listen.”
“I am fond of pigs. Dogs look up to us. Cats look down on us. Pigs treat us as equals.”
“Ending a sentence with a preposition is something up with which I will not put.”
Firefox 1.5 is here
If you’re using Internet Explorer, now is a good time to try Firefox. Click the button.
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Current Firefox users should receive the update automatically.
Smile, you’re on candid camera
NewMexiKen took the day off Tuesday for some routine medical procedures — routine for the doctor and nurses, not so routine for me. (They do 90 a day at this hospital I was told.)
The procedures were a colonoscopy and an endoscopy. In case you haven’t had these pleasures, in each they insert a camera on a flexible tube and take a look around. The colonoscopy is a look at your lower intestine; the endoscopy views your esophagus, stomach and duodenum (a body part I hadn’t considered since high school biology).
Not to put too fine a point on it — and give you “more information than you need” — but to prepare for this double-header I had to go without eating for 36 hours; not even water for the last 12. Furthermore, I had to drink some nasty stuff that proved to be liquid roto-rooter. Prep and anxiety is by far the worst part.
During the procedure they gave me some sedative through an IV (so it sneaks up on you). To my surprise I fell asleep and missed the whole show. I remember coming to for a small amount of pain and some gagging on swallowing the endoscopy tube, but other than that I was gone. The worse part of the whole thing was the IV insertion.
(I did wonder later though if they put me out so they could use the same instrument for both tests without me being any the wiser.)
If you are supposed to get these tests (the colonoscopy is routine after age 50), don’t be like me and put them off indefinitely (10 years) because of fear or anxiety. Do it. Enjoy the nap (and the nap you get after you’re driven home as the sedative sweetly rolls on). Enjoy the encouraging good results if you are fortunate (as most are, and as were mine).
I have photos if you’re interested.
170 years ago today
It’s the birthday of Mark Twain, born Samuel Langhorne Clemens, in Florida, Missouri (1835), who wrote Life on the Mississippi (1883), The Adventures of Huckleberry Finn (1884), and his own favorite, The Personal Recollections of Joan of Arc (1891). He was cynical and irreverent, but he had a tender spot for cats. There were always kittens in the house, and he gave them names like “Sin” and “Sour Mash.” “Mamma has morals,” said his daughter Suzy, “and Papa has cats.” He swore constantly and without shame. His streams of profanity broke his wife’s heart on a daily basis. One day he cut himself shaving, and she heard a string of oaths from the bathroom. She resolved to move him to repentance, and she repeated back to him all the bad words he had just said. He smiled at her and shook his head. “You have the words, Livy,” he said, “but you’ll never learn the tune.” After he published The Adventures of Huckleberry Finn, he found himself awash in cash, which he invested in a typesetting machine that was very complicated and very ingenious and demanded more and more investment and in the end would not work. He had to declare bankruptcy, and he decided to go on a worldwide lecture tour, the proceeds of which he would use to pay back all of his creditors. His visits to Africa and Asia convinced him that a God who allowed Christians to believe that they were better than savages was a God he wanted no part of. He was a funny man and is remembered for his humorous sayings. He said, “It is better to keep you mouth shut and appear stupid than to open it and remove all doubt.” He also said, “Good friends, good books and a sleepy conscience: this is the ideal life.”
Listen to Garrison Keillor recite the above and more.
Best line of the day, so far
“In 1969 I gave up women and alcohol. It was the worst 20 minutes of my life.”
Late soccer star George Best quoted by BBC Sport and reported in Sideline Chatter
Killing the written word by snippets
American University linguistics professor Naomi S. Brown wonders in the Los Angeles Times if we’re “Killing the written word by snippets.” This excerpt:
But today’s college crowd has a tool we did not: the search engine. Want to learn tap dancing in Austin? Lessons are just a few clicks away. So are the words spoken by the White Rabbit in “Alice’s Adventures in Wonderland” or every reference to dogs in “The Canterbury Tales.” Between Microsoft Word’s “find” function, Project Gutenberg, Amazon’s “Search Inside” feature and Google Print, seeking out precise fragments of information has become child’s play.
Search engines are a blessing. Unquestionably, they save all of us vast amounts of time and shoe leather, not to mention their democratizing effect for users without access to substantial book collections. But there is a hitch.
Much as automobiles discourage walking, with undeniable consequences for our health and girth, textual snippets-on-demand threaten our need for the larger works from which they are extracted. Why read “Bowling Alone” — or even the shorter article upon which it builds — when you can lift a page that contains some key words? In an attempt to coax students to search inside real books rather than relying exclusively on the Web for sources, many professors require references to printed works alongside URLs. Now that those “real” full-length publications are increasingly available and searchable online, the distinction between tangible and virtual is evaporating.
Professor Brown concludes: “If we approach the written word primarily through search-and-seizure rather than sustained encounter-and-contemplation, we risk losing a critical element of what it means to be an educated, literate society.” Is she right?
Dolphin games: no mere child’s play?
An interesting report on Dolphin games includes this:
The captive dolphins “produced 317 distinct forms of play behavior during the five years that they were observed,” they wrote.
One calf became adept at “blowing bubbles while swimming upside-down near the bottom of the pool and then chasing and biting each bubble before it reached the surface,” the researchers continued. “She then began to release bubbles while swimming closer and closer to the surface, eventually being so close that she could not catch a single bubble.”
“During all of this, the number of bubbles released was varied, the end result being that the dolphin learned to produce different numbers of bubbles from different depths, the apparent goal being to catch the last bubble right before it reached the surface of the water.”
One assumes the dolphins have also figured out a better tie-breaker than the NFL.
And there’s this wise dolphin-related thought NewMexiKen read some years ago:
Mankind has always assumed that he was more intelligent than dolphins because he had achieved so much — the wheel, New York, wars, and so on — while all the dolphins had ever done was muck about in the water having a good time. But conversely, the dolphins had always believed that they were far more intelligent than man — for precisely the same reasons.
Douglas Adams, The Hitch Hiker’s Guide to the Galaxy
Dolphin article link via BoingBoing.
Now that’s what I call archival quality preservation
This archivist is impressed with the Church of Scientolgy installation in northern New Mexico reported on by local station KRQE, with a follow-up by Richard Leiby in Sunday’s Washington Post:
Secret Flying Saucer Base Found in New Mexico?
Maybe. From the state that gave us Roswell, the epicenter of UFO lore since 1947, comes a report from an Albuquerque TV station about its discovery of strange landscape markings in the remote desert. They’re etched in New Mexico’s barren northern reaches, resemble crop circles and are recognizable only from a high altitude.
Also, they are directly connected to the Church of Scientology. …
The church tried to persuade station KRQE not to air its report last week about the aerial signposts marking a Scientology compound that includes a huge vault “built into a mountainside,” the station said on its Web site. The tunnel was constructed to protect the works of L. Ron Hubbard, the late science-fiction writer who founded the church in the 1950s.
The archiving project, which the church has acknowledged, includes engraving Hubbard’s writings on stainless steel tablets and encasing them in titanium capsules.
The Post has a KRQE aerial photo.
Update: Even better photo from TerraServer.
We’ll be coming back to this post often between now and election day
“If they weren’t blowing them up in Amman, they would be blowing them up in America. We are much better off hunting them down there, and I have no problem at all articulating that whether it’s an election year or not. … I think we’ve made quite a bit of progress in the past eight months.”
Representative Heather Wilson, R-NM (official Congressperson of NewMexiKen)
“One of the great failures of Vietnam was when the politicians started running the war. We can leave or we can stay and work through very difficult circumstances. Just because no one anticipated the things we would be facing is no reason to get out.”
Representative Steve Pearce, R-NM
“Anybody that doesn’t have doubts right now is not paying attention.”
United States Senator Pete Domenici, R-NM
Quotations via AP in The Santa Fe New Mexican
The Grand Old Opry
… began broadcasting on this date in 1925.
At 8 p.m. on November 28, 1925, Hay pronounced himself “The Solemn Old Judge” (though he was actually only 30 years old) and launched, along with championship fiddler, Uncle Jimmy Thompson, what would become the WSM Barn Dance.
Hay’s weekly broadcasts continued and proved enormously popular, and he renamed the show the Grand Ole Opry in 1927. Crowds soon clogged hallways as they gathered to observe the performers, prompting the National Life company to build an acoustically designed auditorium capable of holding 500 fans. When WSM radio increased broadcasting power to 50,000 watts in 1932, most of the United States and parts of Canada could tune into the Opry on Saturday nights, broadening the show’s outreach. …
The Opry went through a number of homes in several parts of Nashville before settling, in 1943, at the Ryman Auditorium, a former religious meeting house built in 1892….